![]() |
Hives |
Hives are an allergic skin reaction causing localized redness, swelling, and itching.
Hives are a reaction of the body’s immune system that causes areas of the skin to swell, itch, and become reddened. (The affected areas are called wheals.) When the reaction is limited to small areas of the skin, it is called urticaria. Involvement of larger areas, such as whole sections of a limb, is called angioedema.
Causes and symptoms
Causes
Hives are an allergic reaction. The body’s immune system is normally responsible for protection from foreign invaders. When it becomes sensitized to normally harmless substances, the resulting reaction is called an allergy. An attack of hives is set off when such a substance, called an allergen, is ingested, inhaled, or otherwise contacted.
It interacts with immune cells called mast cells, which reside in the skin, airways, and digestive system. When mast cells encounter an allergen, they release histamine and other chemicals, both locally and into the bloodstream.